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Elina Ikonen Selected Research

Proteins (Proteins, Gene)

11/2022Seipin localizes at endoplasmic-reticulum-mitochondria contact sites to control mitochondrial calcium import and metabolism in adipocytes.
11/2021Desmosterol suppresses macrophage inflammasome activation and protects against vascular inflammation and atherosclerosis.
10/2020Lysosome Associated Protein Transmembrane 4B-24 Is the Predominant Protein Isoform in Human Tissues and Undergoes Rapid, Nutrient-Regulated Turnover.
1/2019Human PNPLA3-I148M variant increases hepatic retention of polyunsaturated fatty acids.
10/2015LAPTM4B facilitates late endosomal ceramide export to control cell death pathways.
4/2015Elevated levels of StAR-related lipid transfer protein 3 alter cholesterol balance and adhesiveness of breast cancer cells: potential mechanisms contributing to progression of HER2-positive breast cancers.
4/2012Cln5-deficiency in mice leads to microglial activation, defective myelination and changes in lipid metabolism.
6/2007The CCHCR1 (HCR) gene is relevant for skin steroidogenesis and downregulated in cultured psoriatic keratinocytes.

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Elina Ikonen Research Topics

Disease

7Neoplasms (Cancer)
10/2020 - 10/2013
5Atherosclerosis
11/2021 - 10/2006
4Sphingolipidoses (Sphingolipidosis)
10/2019 - 02/2003
4Breast Neoplasms (Breast Cancer)
08/2018 - 09/2012
3Lipodystrophy
11/2022 - 03/2013
3Non-alcoholic Fatty Liver Disease
01/2016 - 04/2014
3Type C Niemann-Pick Disease (Niemann Pick Disease, Type C)
08/2010 - 04/2002
2Inflammation (Inflammations)
11/2021 - 01/2020
2Obesity
10/2019 - 07/2010
2Liver Diseases (Liver Disease)
01/2019 - 04/2014
2Cardiovascular Diseases (Cardiovascular Disease)
04/2014 - 08/2004
2Alzheimer Disease (Alzheimer's Disease)
02/2014 - 10/2013
2Infections
10/2013 - 01/2013
2Lipidoses
11/2004 - 04/2002
1Congenital Generalized Lipodystrophy (Berardinelli-Seip Congenital Lipodystrophy)
11/2022
1Hypercholesterolemia
02/2022
1Hyperlipoproteinemia Type II (Familial Hypercholesterolemia)
02/2022
1Genetic Risk Score
02/2022
1Disease Progression
11/2021
1Atherosclerotic Plaque (Atheroma)
11/2021
17 Hereditary Prostate Cancer
01/2020
1Prostatic Neoplasms (Prostate Cancer)
01/2020
1Neoplasm Metastasis (Metastasis)
01/2020
1Carcinogenesis
01/2020
1Hepatocellular Carcinoma (Hepatoma)
11/2018
1MYH9-Related Disorders
01/2017
1Hyperplasia
05/2016
1Pick Disease of the Brain (Pick's Disease)
01/2016
1Fibrosis (Cirrhosis)
01/2016
1Lysosomal Storage Diseases (Lysosomal Storage Disease)
01/2016
1Fatty Liver
04/2014
1Vascular Diseases (Vascular Disease)
10/2013
1LOM type hereditary motor and sensory Neuropathy
09/2013
1Astrocytoma (Pilocytic Astrocytoma)
03/2013
1Virus Diseases (Viral Diseases)
01/2013
1Dyslipidemias (Dyslipidemia)
12/2012
1Peripheral Arterial Disease
12/2012
1Neuronal Ceroid-Lipofuscinoses (Neuronal Ceroid Lipofuscinosis)
04/2012
1Neurodegenerative Diseases (Neurodegenerative Disease)
04/2012
1Wolman Disease (Wolman's Disease)
12/2008
1Psoriasis (Pustulosis Palmaris et Plantaris)
06/2007
1Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2005
1Insulin Resistance
01/2005

Drug/Important Bio-Agent (IBA)

16CholesterolIBA
11/2021 - 04/2002
15LipidsIBA
01/2020 - 08/2004
8Proteins (Proteins, Gene)FDA Link
11/2022 - 06/2007
3SterolsIBA
11/2021 - 11/2004
3SphingolipidsIBA
10/2015 - 01/2005
2oxidized low density lipoproteinIBA
02/2022 - 01/2016
2DesmosterolIBA
11/2021 - 04/2014
2EnzymesIBA
11/2021 - 04/2014
2Phospholipases (Phospholipase)IBA
01/2019 - 04/2014
2Membrane Proteins (Integral Membrane Proteins)IBA
12/2016 - 04/2015
2Vitamin DFDA LinkGeneric
04/2014 - 06/2007
2Triglycerides (Triacylglycerol)IBA
03/2013 - 08/2010
2Insulin (Novolin)FDA Link
06/2007 - 01/2005
1Adenosine Triphosphate (ATP)IBA
11/2022
1LDL CholesterolIBA
02/2022
1InterferonsIBA
11/2021
1InflammasomesIBA
11/2021
1Protein Isoforms (Isoforms)IBA
10/2020
1SphingomyelinsIBA
10/2019
12-benzyl-3-formylpropanoic acid (BFP)IBA
10/2019
1CarbohydratesIBA
11/2018
1Estrogen ReceptorsIBA
08/2018
1Phenobarbital (Luminal)FDA Link
08/2018
1TamoxifenFDA LinkGeneric
08/2018
1Fibrillar CollagensIBA
01/2016
1CeramidesIBA
10/2015
1lipid transfer protein (glycolipid transfer protein)IBA
04/2015
1src-Family KinasesIBA
04/2015
1Messenger RNA (mRNA)IBA
04/2015
13-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA)IBA
04/2015
1Oxidoreductases (Dehydrogenase)IBA
04/2015
1SqualeneIBA
04/2014
1lathosterolIBA
02/2014
1LDL Receptors (LDL Receptor)IBA
02/2014
1Filipin (Filipin III)IBA
01/2013
1Ketoconazole (Nizoral)FDA LinkGeneric
01/2013
1LigandsIBA
01/2013
1IntegrinsIBA
01/2013
1LanosterolIBA
01/2013
1CollagenIBA
01/2013
1Nystatin (Mycostatin)FDA LinkGeneric
01/2013
1oxysterol binding proteinIBA
12/2012
1SphingosineIBA
09/2012
1Fingolimod Hydrochloride (FTY720)FDA Link
03/2010
1Dehydroepiandrosterone (DHEA)IBA
12/2008
1Cyclosporine (Ciclosporin)FDA LinkGeneric
06/2007
1Hormones (Hormone)IBA
06/2007
1Estrogens (Estrogen)FDA Link
06/2007
1Epidermal Growth Factor (EGF)IBA
06/2007
1SteroidsIBA
06/2007
1Insulin ReceptorIBA
11/2005
1Membrane LipidsIBA
01/2005

Therapy/Procedure

2Therapeutics
08/2018 - 10/2015
1Mammaplasty (Breast Reconstruction)
09/2012